What Happens If My TB Skin Test Is Positive? Next Steps & More

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Getting a positive TB skin test result can definitely spark some worry. What happens if my TB skin test is positive? It means you’ve likely been exposed to the bacteria that cause tuberculosis, but don’t panic just yet. A positive TB skin test doesn’t automatically mean you have active TB, which is when you experience symptoms and are contagious. Often, it means you have a latent TB infection.

What happens if my TB skin test is positive, and how is it different from active TB? Having latent TB means the TB germs are present in your body, but they are inactive. You won’t feel sick or show any symptoms. But, this inactive form can transition into active TB if not addressed, particularly if your immune system weakens. This is why taking the right steps after a positive test is critical.

Table of Contents:

Understanding TB Skin Tests

To really understand the significance of a positive TB skin test, let’s break down what a TB skin test — also known as the tuberculin skin test or Mantoux test — actually does. This test isn’t looking for the active disease itself but for your body’s immune response to the bacteria, Mycobacterium tuberculosis . It’s a common test that helps healthcare providers assess your risk.

How a TB Skin Test Works

During the test, a tiny amount of a substance called tuberculin, a purified protein derivative from the TB bacteria, is injected just below the skin of your forearm. This creates a small, pale bump at the injection site. You will need to spend time at your appointment to receive the injection.

You return to your health care provider within 48 to 72 hours to have the skin test read. This allows them to examine the site and interpret the results. They are checking for a reaction called induration. Induration is any hardening and swelling at the injection spot.

The size of this reaction is key. The larger the induration, the more likely you are to have a TB infection. However, several factors can influence how a positive reaction is interpreted, including age, overall health, and previous BCG vaccination. It’s best to talk to your primary care provider as they will assess your specific circumstances.

Decoding a Positive TB Skin Test

So, what happens if your TB skin test turns out positive? Your healthcare provider will be the best person to explain the results. However, I can walk you through the basics. A positive TB skin test doesn’t instantly signify you have active TB. Let’s talk about why.

Possible Scenarios of a Positive TB Skin Test Result

  1. Latent TB Infection : As previously mentioned, latent TB is the most common reason for a positive skin test. This is especially true in the US, where active TB rates are generally lower. If this is the case, your doctor will discuss treatment options to stop the infection from transitioning into active TB disease, even if you aren’t feeling ill. 1 in 10 people with inactive TB will develop active TB if left untreated, according to the Centers for Disease Control and Prevention . This makes treatment essential.
  2. Previous Exposure : Sometimes, a positive skin test results from previous exposure to the bacteria, even if the infection is now gone. It’s akin to how your body “remembers” past illnesses.
  3. BCG Vaccination : If you received the BCG vaccine against TB, particularly as a child in a country with higher TB rates, you might show a positive reaction, even without an infection.

Follow-up: Next Steps After a Positive Test

Your healthcare provider will usually recommend further tests to determine whether you have active or latent TB if you have a positive skin test result. These disease tests help determine what is going on in your body.

Additional Testing After a Positive Skin Test

The following tests may be used to help determine if you have active or latent TB.

  1. Chest X-ray : A chest x-ray helps to spot any signs of active TB in your lungs, such as the white spots indicative of an immune response. If you’re experiencing symptoms like a persistent cough or weight loss, this can further aid in the diagnosis.
  2. TB Blood Tests : These tests directly detect TB bacteria in the blood and are sometimes preferred. They are often used if there’s a history of BCG vaccination, as they can differentiate between a test reaction from the vaccine and an actual infection. They offer greater accuracy and, unlike the skin test, can often differentiate between latent TB infection and active TB disease.
  3. Sputum Tests : If the chest x-ray suggests active TB, sputum tests are carried out. You’ll be asked to provide a sample of your sputum (phlegm) coughed up from the lungs. This is then examined in a laboratory for the presence of TB bacteria, confirming the diagnosis and helping doctors choose the right medications.

Treating a Positive TB Skin Test Result

Your treatment will be determined by the findings of your further tests, such as a chest X-ray, which helps doctors visualize any changes in your lungs suggestive of TB infection. They will then use this information alongside the blood or sputum tests (if taken) to guide the next steps in your care. Let’s look at the common treatment options based on the outcomes.

Latent TB Infection Treatment

If you have a positive TB test result but no active TB signs or evidence of active infection in further testing, your doctor might suggest treatment for latent TB. This preventative measure aims to eradicate the bacteria before it becomes active and contagious.

Latent TB is commonly treated with a combination of medications typically taken over 3 to 4 months. According to the CDC, a healthcare provider may suggest longer, 9-month treatment options if the shorter courses aren’t feasible. Your healthcare professional will choose a treatment regimen best suited for your individual case. They will closely monitor your progress to manage potential side effects.

Active TB Disease Treatment

Treatment for active TB disease usually lasts longer than that for latent infection. Active TB disease treatment involves various medications, potentially for several months, to eliminate the bacteria completely. These medicines fight the TB germs, often taken as a combination, and must be taken consistently throughout the treatment period to be successful.

While taking the medication, you’ll need regular check-ups to monitor the effectiveness of the treatment and manage any potential side effects. It’s essential to follow your doctor’s instructions carefully and finish the full course of antibiotics, even if you start to feel better before completing the medication.

FAQs about What happens if my tb skin test is positive

What should I ask my doctor if I have a positive TB skin test?

If your TB skin test result is positive, have a conversation with your doctor to understand what this signifies for you. They’ll be able to address any specific questions or concerns you might have about your individual circumstances.

What are the symptoms of active tuberculosis?

Active tuberculosis symptoms often include a persistent cough that lingers for more than 3 weeks, unexplained weight loss, coughing up blood, fever, chills, and night sweats. If you experience these, seeking medical advice promptly is essential.

Conclusion

What happens if my TB skin test is positive? It means seeking advice from a healthcare professional is a must. They are the right people to assess your individual circumstances, offer personalized recommendations, and ensure you receive the proper guidance for your particular case.

While receiving a positive TB skin test might feel unsettling, understanding what it means and the potential next steps will help you navigate this situation. By working closely with your healthcare provider, you can make informed decisions about your health.

author avatar
Jose Rossello, MD, PhD, MHCM
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