The contents of this website are supervised by Jose Rossello, MD, PhD, MCHM specializing in Preventive Medicine and Public Health.
Learn more about Jose Rossello.
This large European study established age- and sex-specific reference values for handgrip strength in adults aged 50 and older across 27 countries, highlighting peak strength in the early 50s followed by decline with age. These ...
Early removal of the thymus gland in early life leads to a premature aging of T cells, causing inflammation in visceral fat tissue and impairing glucose metabolism, which can contribute to glucose intolerance and increased ...
Klotho is a kidney-produced protein with powerful anti-aging effects that regulate phosphate and calcium balance, protect against oxidative stress, and influence key metabolic pathways. Its levels decline with age and kidney dysfunction, contributing to age-related ...
Low calf circumference is a common issue among older adults, often associated with poor muscle mass and increased risk of health complications like multimorbidity. This condition is not solely linked to age, as different groups ...
Skipping meals, especially during early and midlife, is linked to an increased risk of physical frailty in later years, highlighting the importance of establishing regular eating habits well before old age. Maintaining consistent meal patterns ...
A novel selenium supplement using redox-responsive nanoparticles (SeMSNs) has been shown to extend lifespan and delay aging-related decline in multiple organs in aged mice by maintaining calcium balance and regulating the Sik1 pathway. This approach ...